BDBM808041 US12629358, Compound C16

SMILES CO[C@]1(C(=O)N[C@@H](C)c2ccc(-n3cc(F)cn3)nc2)CC[C@@H](c2nc(Nc3cc(C)[nH]n3)cc(C)c2C#N)CC1

InChI Key InChIKey=JUGDQGUAHSRUMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808041   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 808041BDBM808041(US12629358, Compound C16)
Affinity DataIC50: 180nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/25/2018
Entry Details
US Patent