BDBM808049 US12630511, Example 5

SMILES CN1CCN(C2CCN(c3ccc(-c4cccc(C(=O)N[C@@H](c5cc6ccccc6[nH]5)c5cc(F)ccc5O)c4)cc3)CC2)CC1

InChI Key InChIKey=DSZQDVYUKLLCII-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808049   

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 808049BDBM808049(US12630511, Example 5)
Affinity DataIC50: 2.60E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent