BDBM808054 US12630511, Example 10

SMILES O=C(N[C@@H](c1cc2ccccc2[nH]1)c1cc(F)ccc1O)c1cccc(-c2ccc(N3CCCC3)cc2)c1

InChI Key InChIKey=LLTPTQHPKCDXCL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808054   

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 808054BDBM808054(US12630511, Example 10)
Affinity DataIC50: 5.90E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent