BDBM808056 US12630511, Example 12

SMILES N[C@H]1CCN(c2ccc(-c3cccc(C(=O)N[C@@H](c4cc5ccccc5[nH]4)c4cc(F)ccc4O)c3)cc2)C1

InChI Key InChIKey=PLHDKHPNWUVRTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808056   

TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 808056BDBM808056(US12630511, Example 12)
Affinity DataIC50: 180nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent