BDBM808170 (R)-2-(3-((6-((6-(3-(2-ethoxyphenoxy)piperidin-1-yl)pyrazin-2-yl)amino)pyridin-2-yl)oxy)phenyl)acetic Acid::US12630528, Example 95

SMILES CCOc1ccccc1O[C@@H]1CCCN(c2cncc(Nc3cccc(Oc4cccc(CC(=O)O)c4)n3)n2)C1

InChI Key InChIKey=VQYOZUVUHDLKLP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808170   

TargetDiacylglycerol O-acyltransferase 2(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 808170BDBM808170((R)-2-(3-((6-((6-(3-(2-ethoxyphenoxy)piperidin-1-y...)
Affinity DataIC50: 83nMAssay Description:In vitro kinase assays described below can be used to determine the activity of a test compound for inhibiting the activity of JAK1 kinase. The test ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/16/2019
Entry Details
US Patent