BDBM808185 (R)-3-(3-(6-((6-(3-(2-ethoxyphenoxy)piperidin-1-yl)pyrazin-2-yl)amino)-4-(trifluoromethyl)pyridin-2-yl)phenyl)-2,2-dimethylpropanoic Acid::US12630528, Example 110

SMILES CCOc1ccccc1O[C@@H]1CCCN(c2cncc(Nc3cc(C(F)(F)F)cc(-c4cccc(CC(C)(C)C(=O)O)c4)n3)n2)C1

InChI Key InChIKey=OMKGAWYWUIPHAY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808185   

TargetDiacylglycerol O-acyltransferase 2(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 808185BDBM808185((R)-3-(3-(6-((6-(3-(2-ethoxyphenoxy)piperidin-1-yl...)
Affinity DataIC50: 170nMAssay Description:In vitro kinase assays described below can be used to determine the activity of a test compound for inhibiting the activity of JAK2 kinase. The test ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/16/2019
Entry Details
US Patent