BDBM808203 2-((S)-1-(2-((6-((R)-3-(2-ethoxyphenoxy)piperidin-1-yl)pyrazin-2-yl)amino)pyrimidin-4-yl)piperidin-3-yl)acetic Acid::US12630528, Example 128

SMILES CCOc1ccccc1O[C@@H]1CCCN(c2cncc(Nc3nccc(N4CCC[C@@H](CC(=O)O)C4)n3)n2)C1

InChI Key InChIKey=ISQMXFDJONGEKV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808203   

TargetDiacylglycerol O-acyltransferase 2(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 808203BDBM808203(2-((S)-1-(2-((6-((R)-3-(2-ethoxyphenoxy)piperidin-...)
Affinity DataIC50: 160nMAssay Description:In vitro kinase assays described below can be used to determine the activity of a test compound for inhibiting the activity of JAK2 kinase. The test ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/16/2019
Entry Details
US Patent