BDBM808240 (R)-3-(3-(2-((6-(3-((3-ethoxypyridin-2-yl)oxy)piperidin-1-yl)pyrazin-2-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)phenyl)-2,2-dimethylpropanoic Acid::US12630528, Example 165

SMILES CCOc1cccnc1O[C@@H]1CCCN(c2cncc(Nc3ncc(C(F)(F)F)c(-c4cccc(CC(C)(C)C(=O)O)c4)n3)n2)C1

InChI Key InChIKey=BWWCMLRNNBCOMK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808240   

TargetDiacylglycerol O-acyltransferase 2(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 808240BDBM808240((R)-3-(3-(2-((6-(3-((3-ethoxypyridin-2-yl)oxy)pipe...)
Affinity DataIC50: 64nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/16/2019
Entry Details
US Patent