BDBM808245 (R)-3-(3-(4-((6-(3-(2-ethoxyphenoxy)piperidin-1-yl)pyrazin-2-yl)amino)pyrimidin-2-yl)phenyl)-2,2-dimethylpropanoic Acid::US12630528, Example 170

SMILES CCOc1ccccc1O[C@@H]1CCCN(c2cncc(Nc3ccnc(-c4cccc(CC(C)(C)C(=O)O)c4)n3)n2)C1

InChI Key InChIKey=DHCOMVQPWCTKEJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808245   

TargetDiacylglycerol O-acyltransferase 2(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 808245BDBM808245((R)-3-(3-(4-((6-(3-(2-ethoxyphenoxy)piperidin-1-yl...)
Affinity DataIC50: 250nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/16/2019
Entry Details
US Patent