BDBM808246 (R)-3-(3-(4-((6-(3-((3-ethoxypyridin-2-yl)oxy)piperidin-1-yl)pyrazin-2-yl)amino)pyrimidin-2-yl)phenyl)-2,2-dimethylpropanoic Acid::US12630528, Example 171

SMILES CCOc1cccnc1O[C@@H]1CCCN(c2cncc(Nc3ccnc(-c4cccc(CC(C)(C)C(=O)O)c4)n3)n2)C1

InChI Key InChIKey=ZJDUSDSFWMYZDL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808246   

TargetDiacylglycerol O-acyltransferase 2(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 808246BDBM808246((R)-3-(3-(4-((6-(3-((3-ethoxypyridin-2-yl)oxy)pipe...)
Affinity DataIC50: 240nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/16/2019
Entry Details
US Patent