BDBM808319 Preparation of 4-(3-methyl-6-(7-methylimidazo[1,2-a]pyridin-6-ylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)benzonitrile (Ex. 73)::US12630565, Example 73

SMILES N#Cc1ccc(-n2nc(C)c3cnc(Nc4cn5ccnc5cc4C)nc32)cc1

InChI Key InChIKey=JZZVHSRDRSOWMX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808319   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Dizal (Jiangsu) Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 808319BDBM808319(Preparation of 4-(3-methyl-6-(7-methylimidazo[1,2-...)
Affinity DataIC50: 1.30nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/4/2017
Entry Details
US Patent