BDBM808331 Preparation of 1-((1R,3r,5S)-8-oxa-bicyclo[3.2.1]octan-3-yl)-3-methyl-N-(7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine::US12630565, Example 106

SMILES Cc1cc2ncnn2cc1Nc1ncc2c(C)nn([C@H]3C[C@H]4CC[C@@H](C3)O4)c2n1

InChI Key InChIKey=JVDPVDKDBDKULN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808331   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Dizal (Jiangsu) Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 808331BDBM808331(Preparation of 1-((1R,3r,5S)-8-oxa-bicyclo[3.2.1]o...)
Affinity DataIC50: 0.900nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/4/2017
Entry Details
US Patent