BDBM808339 1-(3-methoxycyclopentyl)-3-methyl-N-(7- methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H- pyrazolo[3,4-d]pyrimidin-6-amine (isomer 3)::US12630565, Example 110

SMILES COC1CCC(n2nc(C)c3cnc(Nc4cn5ncnc5cc4C)nc32)C1

InChI Key InChIKey=JQCYIUZTDGGJQO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808339   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Dizal (Jiangsu) Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 808339BDBM808339(1-(3-methoxycyclopentyl)-3-methyl-N-(7- methyl-[1,...)
Affinity DataIC50: 1.80nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/4/2017
Entry Details
US Patent