BDBM808344 1-(6,6-difluorospiro[3.3]heptan-2-yl)-3-methyl- N-(7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)- 1H-pyrazolo[3,4-d]pyrimidin-6-amine::US12630565, Example 41

SMILES Cc1cc2ncnn2cc1Nc1ncc2c(C)nn(C3CC4(C3)CC(F)(F)C4)c2n1

InChI Key InChIKey=XJWIPANHGHOZKN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808344   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Dizal (Jiangsu) Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 808344BDBM808344(1-(6,6-difluorospiro[3.3]heptan-2-yl)-3-methyl- N-...)
Affinity DataIC50: 1.40nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/4/2017
Entry Details
US Patent