BDBM808348 Preparation of 3-methyl-N-(7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-1-(spiro[3.3]heptan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine (Ex. 43)::US12630565, Example 43

SMILES Cc1cc2ncnn2cc1Nc1ncc2c(C)nn(C3CC4(CCC4)C3)c2n1

InChI Key InChIKey=YWCLTURYBWPXSM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808348   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Dizal (Jiangsu) Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 808348BDBM808348(Preparation of 3-methyl-N-(7-methyl-[1,2,4]triazol...)
Affinity DataIC50: 1.5nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/4/2017
Entry Details
US Patent