BDBM808489 2-(6-chloropyridin- 3-yl)-N-(4-(6- methoxy-7-((1-(2- methoxyethyl) piperidin-4- yl)methoxy)quinazolin- 4- yl)phenyl)acetamide::US20260138959, Example 113

SMILES COCCN1CCC(COc2cc3ncnc(-c4ccc(NC(=O)Cc5ccc(Cl)nc5)cc4)c3cc2OC)CC1

InChI Key InChIKey=UVWVMTXMOXERCU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808489   

TargetPlatelet-derived growth factor receptor beta(Human)
Voronoi

US Patent
LigandChemical structure of BindingDB Monomer ID 808489BDBM808489(2-(6-chloropyridin- 3-yl)-N-(4-(6- methoxy-7-((1-(...)
Affinity DataIC50: 50nMAssay Description:In order to evaluate the inhibitory activity of the compounds synthesized according to the above examples on PDGFR-α(wt), PDGFR-β(wt), c-KIT(wt), and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent