BDBM808491 N-(4-(7-((1- isopropylpiperidin- 4-yl)methoxy)-6- methoxyquinazolin-4- yl)phenyl)-2-(6- methoxypyridin-3- yl)acetamide::US20260138959, Example 116

SMILES COc1ccc(CC(=O)Nc2ccc(-c3ncnc4cc(OCC5CCN(C(C)C)CC5)c(OC)cc34)cc2)cn1

InChI Key InChIKey=JASIEMHXCXLRRS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808491   

TargetPlatelet-derived growth factor receptor beta(Human)
Voronoi

US Patent
LigandChemical structure of BindingDB Monomer ID 808491BDBM808491(N-(4-(7-((1- isopropylpiperidin- 4-yl)methoxy)-6- ...)
Affinity DataIC50: 50nMAssay Description:In order to evaluate the inhibitory activity of the compounds synthesized according to the above examples on PDGFR-α(wt), PDGFR-β(wt), c-KIT(wt), and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent