BDBM808494 2-(4-fluorophen- yl)-N-(4-(6- hydroxy-7-meth- oxyquinazolin-4- yl)phenyl)acet- amide::US20260138959, Example 124

SMILES COc1cc2ncnc(-c3ccc(NC(=O)Cc4ccc(F)cc4)cc3)c2cc1O

InChI Key InChIKey=NSVSXCDSSWCEEZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 808494   

TargetPlatelet-derived growth factor receptor alpha(Human)
Voronoi

US Patent
LigandChemical structure of BindingDB Monomer ID 808494BDBM808494(2-(4-fluorophen- yl)-N-(4-(6- hydroxy-7-meth- oxyq...)
Affinity DataIC50: 50nMAssay Description:In order to evaluate the inhibitory activity of the compounds synthesized according to the above examples on PDGFR-α(wt), PDGFR-β(wt), c-KIT(wt), and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Voronoi

US Patent
LigandChemical structure of BindingDB Monomer ID 808494BDBM808494(2-(4-fluorophen- yl)-N-(4-(6- hydroxy-7-meth- oxyq...)
Affinity DataIC50: 300nMAssay Description:In order to evaluate the inhibitory activity of the compounds synthesized according to the above examples on PDGFR-α(wt), PDGFR-β(wt), c-KIT(wt), and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent