BDBM808496 US20260138959, Example 130::tert-butyl 3-(((7- methoxy-4-(4-(2- (4-(trifluorometh- yl)phenyl)acet- amido)phenyl)- quinazolin-6-yl)- oxy)methyl)piperi- din-1-carboxylate

SMILES COc1cc2ncnc(-c3ccc(NC(=O)Cc4ccc(C(F)(F)F)cc4)cc3)c2cc1OCC1CCCN(C(=O)OC(C)(C)C)C1

InChI Key InChIKey=LDSNGDFGHXTWCT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808496   

TargetPlatelet-derived growth factor receptor beta(Human)
Voronoi

US Patent
LigandChemical structure of BindingDB Monomer ID 808496BDBM808496(tert-butyl 3-(((7- methoxy-4-(4-(2- (4-(trifluorom...)
Affinity DataIC50: 50nMAssay Description:In order to evaluate the inhibitory activity of the compounds synthesized according to the above examples on PDGFR-α(wt), PDGFR-β(wt), c-KIT(wt), and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent