BDBM808500 N-(4-(7-methoxy- 6-(piperidin-4- yloxy)quinazolin- 4-yl)phenyl)-2-(4- (trifluoromethyl)- phenyl)acetamide::US20260138959, Example 140

SMILES COc1cc2ncnc(-c3ccc(NC(=O)Cc4ccc(C(F)(F)F)cc4)cc3)c2cc1OC1CCNCC1

InChI Key InChIKey=UTRGAOFDCGZOCF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 808500   

TargetPlatelet-derived growth factor receptor alpha(Human)
Voronoi

US Patent
LigandChemical structure of BindingDB Monomer ID 808500BDBM808500(N-(4-(7-methoxy- 6-(piperidin-4- yloxy)quinazolin-...)
Affinity DataIC50: 50nMAssay Description:In order to evaluate the inhibitory activity of the compounds synthesized according to the above examples on PDGFR-α(wt), PDGFR-β(wt), c-KIT(wt), and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Voronoi

US Patent
LigandChemical structure of BindingDB Monomer ID 808500BDBM808500(N-(4-(7-methoxy- 6-(piperidin-4- yloxy)quinazolin-...)
Affinity DataIC50: 50nMAssay Description:In order to evaluate the inhibitory activity of the compounds synthesized according to the above examples on PDGFR-α(wt), PDGFR-β(wt), c-KIT(wt), and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent