BDBM808506 N-(4-(7-methoxy- 6-(3-((1S,4S)-5- methyl-2,5-diaza- bicyclo[2.2.1] heptane-2-yl)- propoxy)quinaz- olin-4-yl)phenyl)- 2-(4-(trifluoro- methyl)phenyl)- acetamide::US20260138959, Example 158

SMILES COc1cc2ncnc(-c3ccc(NC(=O)Cc4ccc(C(F)(F)F)cc4)cc3)c2cc1OCCCN1C[C@@H]2C[C@H]1CN2C

InChI Key InChIKey=KYXFLLHAGWYFCT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808506   

TargetPlatelet-derived growth factor receptor beta(Human)
Voronoi

US Patent
LigandChemical structure of BindingDB Monomer ID 808506BDBM808506(N-(4-(7-methoxy- 6-(3-((1S,4S)-5- methyl-2,5-diaza...)
Affinity DataIC50: 50nMAssay Description:In order to evaluate the inhibitory activity of the compounds synthesized according to the above examples on PDGFR-α(wt), PDGFR-β(wt), c-KIT(wt), and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent