BDBM808507 N-(4-(6-(3-(hexa- hydropyrrolo[1,2- a]pyrazin-2(1H)- yl)propoxy)-7- methoxyquinaz- olin-4-yl)phenyl)- 2-(4-(trifluoro- methyl)phenyl)- acetamide::US20260138959, Example 161

SMILES COc1cc2ncnc(-c3ccc(NC(=O)Cc4ccc(C(F)(F)F)cc4)cc3)c2cc1OCCCN1CCN2CCCC2C1

InChI Key InChIKey=DFRSLWGFNDEXSP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808507   

TargetPlatelet-derived growth factor receptor beta(Human)
Voronoi

US Patent
LigandChemical structure of BindingDB Monomer ID 808507BDBM808507(N-(4-(6-(3-(hexa- hydropyrrolo[1,2- a]pyrazin-2(1H...)
Affinity DataIC50: 50nMAssay Description:In order to evaluate the inhibitory activity of the compounds synthesized according to the above examples on PDGFR-α(wt), PDGFR-β(wt), c-KIT(wt), and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent