BDBM808508 2-(benzo[d][1,3] dioxol-5-yl)-N- (2-fluoro-4-(6- methoxy-7-(3-(4- methylpiperazin- 1-yl)propoxy)- quinazolin-4-yl)- phenyl)acetamide::US20260138959, Example 163

SMILES COc1cc2c(-c3ccc(NC(=O)Cc4ccc5c(c4)OCO5)c(F)c3)ncnc2cc1OCCCN1CCN(C)CC1

InChI Key InChIKey=SJFKIHKLMKTTJZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808508   

TargetPlatelet-derived growth factor receptor beta(Human)
Voronoi

US Patent
LigandChemical structure of BindingDB Monomer ID 808508BDBM808508(2-(benzo[d][1,3] dioxol-5-yl)-N- (2-fluoro-4-(6- m...)
Affinity DataIC50: 50nMAssay Description:In order to evaluate the inhibitory activity of the compounds synthesized according to the above examples on PDGFR-α(wt), PDGFR-β(wt), c-KIT(wt), and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent