BDBM808511 N-(benzo[d][1,3] dioxol-5-ylmethyl)- 4-(6-methoxy-7-(3- (4-methylpiperazin- 1-yl)propoxy)quin- azolin-4-yl)benz- amide::US20260138959, Example 166

SMILES COc1cc2c(-c3ccc(C(=O)NCc4ccc5c(c4)OCO5)cc3)ncnc2cc1OCCCN1CCN(C)CC1

InChI Key InChIKey=SWGVFPQGLYWZMM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808511   

TargetPlatelet-derived growth factor receptor beta(Human)
Voronoi

US Patent
LigandChemical structure of BindingDB Monomer ID 808511BDBM808511(N-(benzo[d][1,3] dioxol-5-ylmethyl)- 4-(6-methoxy-...)
Affinity DataIC50: 50nMAssay Description:In order to evaluate the inhibitory activity of the compounds synthesized according to the above examples on PDGFR-α(wt), PDGFR-β(wt), c-KIT(wt), and...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent