BDBM808644 7-(2-fluoro-6-methyl-phenyl)-N5-[(1- methylazetidin-3- yl)methyl]isoquinoline-3,5-diamine::US12637428, Example E72

SMILES Cc1cccc(F)c1-c1cc(NCC2CN(C)C2)c2cc(N)ncc2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 808644   

TargetSerine/threonine-protein kinase SIK2(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 808644BDBM808644(7-(2-fluoro-6-methyl-phenyl)-N5-[(1- methylazetidi...)
Affinity DataKi:  0.117nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK1(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 808644BDBM808644(7-(2-fluoro-6-methyl-phenyl)-N5-[(1- methylazetidi...)
Affinity DataKi:  0.627nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK3(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 808644BDBM808644(7-(2-fluoro-6-methyl-phenyl)-N5-[(1- methylazetidi...)
Affinity DataKi:  1.29nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 808644BDBM808644(7-(2-fluoro-6-methyl-phenyl)-N5-[(1- methylazetidi...)
Affinity DataKi:  1.83nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 808644BDBM808644(7-(2-fluoro-6-methyl-phenyl)-N5-[(1- methylazetidi...)
Affinity DataKi:  40.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetEphrin type-A receptor 2(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 808644BDBM808644(7-(2-fluoro-6-methyl-phenyl)-N5-[(1- methylazetidi...)
Affinity DataKi:  153nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent