BDBM808657 7-(2-fluoro-6-methyl-phenyl)-N5- [(3R)-1-methyl-3- piperidyl]isoquinoline-3,5-diamine::US12637428, Example E85

SMILES Cc1cccc(F)c1-c1cc(N[C@@H]2CCCN(C)C2)c2cc(N)ncc2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 808657   

TargetSerine/threonine-protein kinase SIK2(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 808657BDBM808657(7-(2-fluoro-6-methyl-phenyl)-N5- [(3R)-1-methyl-3-...)
Affinity DataKi:  0.0910nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK1(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 808657BDBM808657(7-(2-fluoro-6-methyl-phenyl)-N5- [(3R)-1-methyl-3-...)
Affinity DataKi:  0.611nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK3(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 808657BDBM808657(7-(2-fluoro-6-methyl-phenyl)-N5- [(3R)-1-methyl-3-...)
Affinity DataKi:  1.62nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 808657BDBM808657(7-(2-fluoro-6-methyl-phenyl)-N5- [(3R)-1-methyl-3-...)
Affinity DataKi:  7.38nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 808657BDBM808657(7-(2-fluoro-6-methyl-phenyl)-N5- [(3R)-1-methyl-3-...)
Affinity DataKi:  40.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetEphrin type-A receptor 2(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 808657BDBM808657(7-(2-fluoro-6-methyl-phenyl)-N5- [(3R)-1-methyl-3-...)
Affinity DataKi:  258nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent