BDBM808711 US12637430, Example 2::US12637440, Example 1

SMILES Cn1nccc1C(=O)N[C@H](C(=O)Nc3ccc(C2CCOCC2)cc3)C(C4CCC4)C5(C)CC5

InChI Key InChIKey=FXBDXNWRMZTXIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 808711   

TargetDiacylglycerol O-acyltransferase 2(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 808711BDBM808711(US12637440, Example 1 | US12637430, Example 2)
Affinity DataIC50: 45nMAssay Description:In vitro DGAT2 analysis was perfomed used a Phospholipid Flast Pate (Perkin Elmer) based on the principle of SPA (Scintillation Proximity Assay). Fi...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
4/12/2021
Entry Details
US Patent

TargetInterleukin-17A(Human)
HitGen

US Patent
LigandChemical structure of BindingDB Monomer ID 808711BDBM808711(US12637440, Example 1 | US12637430, Example 2)
Affinity DataIC50: 66nMAssay Description:The inhibition of receptor-ligand binding by human IL-17A inhibitors was quantified by competitive ELISA. 0.2 ug/ml of IL-17A (Sino Biological Inc. ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent