BDBM808739 US12637430, Example 42::US12637440, Example 29

SMILES CCc1nocc1C(=O)N[C@H](C(=O)Nc3ccc(c2c(C)n[nH]c2C)nc3)C(C4CC4)C5CC5

InChI Key InChIKey=JZOAHSPEPMFSLT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 808739   

TargetDiacylglycerol O-acyltransferase 2(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 808739BDBM808739(US12637440, Example 29 | US12637430, Example 42)
Affinity DataIC50: 18nMAssay Description:In vitro DGAT2 analysis was perfomed used a Phospholipid Flast Pate (Perkin Elmer) based on the principle of SPA (Scintillation Proximity Assay). Fi...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
4/12/2021
Entry Details
US Patent

TargetInterleukin-17A(Human)
HitGen

US Patent
LigandChemical structure of BindingDB Monomer ID 808739BDBM808739(US12637440, Example 29 | US12637430, Example 42)
Affinity DataIC50: 170nMAssay Description:The inhibition of receptor-ligand binding by human IL-17A inhibitors was quantified by competitive ELISA. 0.2 ug/ml of IL-17A (Sino Biological Inc. ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent