BDBM808745 US12637430, Example 27

SMILES CN1C(=O)C2(CCOCC2)c2ccc(NC(=O)[C@@H](NC(=O)c3ccnn3C)[C@H](c3ccccc3Cl)C3(C)CC3)cc21

InChI Key InChIKey=USROIHCXOQKDAV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808745   

TargetInterleukin-17A(Human)
HitGen

US Patent
LigandChemical structure of BindingDB Monomer ID 808745BDBM808745(US12637430, Example 27)
Affinity DataIC50: 104nMAssay Description:The inhibition of receptor-ligand binding by human IL-17A inhibitors was quantified by competitive ELISA. 0.2 ug/ml of IL-17A (Sino Biological Inc. ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent