BDBM808758 US12637430, Example 61

SMILES Cn1nccc1C(=O)N[C@H](C(=O)Nc3ccc(N2CCOCC2)nc3)[C@H](c4ccccc4Cl)C5(C)CC5

InChI Key InChIKey=ZRXCCAQIXUPLIB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 808758   

TargetInterleukin-17A(Human)
HitGen

US Patent
LigandChemical structure of BindingDB Monomer ID 808758BDBM808758(US12637430, Example 61)
Affinity DataIC50: 7nMAssay Description:The inhibition of receptor-ligand binding by human IL-17A inhibitors was quantified by competitive ELISA. 0.2 ug/ml of IL-17A (Sino Biological Inc. ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetInterleukin-17A(Human)
HitGen

US Patent
LigandChemical structure of BindingDB Monomer ID 808758BDBM808758(US12637430, Example 61)
Affinity DataIC50: 327nMAssay Description:The inhibition of receptor-ligand binding by human IL-17A inhibitors was quantified by competitive ELISA. 0.2 ug/ml of IL-17A (Sino Biological Inc. ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent