BDBM808759 US12637430, Example 62::US12637440, Example 49

SMILES Cn1nccc1C(=O)N[C@H](C(=O)Nc3ccc(C2CCOCC2)cc3)[C@H](c4ccccc4Cl)C5(C)CC5

InChI Key InChIKey=UBCQXMHWAVHKEI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 808759   

TargetInterleukin-17A(Human)
HitGen

US Patent
LigandChemical structure of BindingDB Monomer ID 808759BDBM808759(US12637440, Example 49 | US12637430, Example 62)
Affinity DataIC50: 56nMAssay Description:The inhibition of receptor-ligand binding by human IL-17A inhibitors was quantified by competitive ELISA. 0.2 ug/ml of IL-17A (Sino Biological Inc. ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent

TargetDiacylglycerol O-acyltransferase 2(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 808759BDBM808759(US12637440, Example 49 | US12637430, Example 62)
Affinity DataIC50: 100nMAssay Description:In vitro DGAT2 analysis was perfomed used a Phospholipid Flast Pate (Perkin Elmer) based on the principle of SPA (Scintillation Proximity Assay). Fi...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
4/12/2021
Entry Details
US Patent