BDBM808948 US12637454, Example 59::[(7S,9aR)-7-(3,4-difluorophenyl)-7-

SMILES COc1cccc(C(=O)N2CCN3C[C@@](O)(c4ccc(F)c(F)c4)CC[C@@H]3C2)c1Cl

InChI Key InChIKey=CAXGHTRYRWRCGN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808948   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 808948BDBM808948([(7S,9aR)-7-(3,4-difluorophenyl)-7- | US12637454, ...)
Affinity DataIC50: 11.2nMAssay Description:The asssay is hereinafter abbreviated "2-AG assay". The 2-AG assay was carried out in 384 well assay plated (PP, Greiner Cat #784201) in a total vol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/20/2025
Entry Details
US Patent