BDBM808964 US12637469, Compound 5

SMILES c1cn2c(n1)c(Nc1ccc(N3CCN(C4COC4)CC3)cc1)nc1ccc(-c3cn[nH]c3)cc12

InChI Key InChIKey=KWGQUGBBTGHOHK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 808964   

TargetTyrosine-protein kinase SYK(Human)
Ocumension Therapeutics (Suzhou) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 808964BDBM808964(US12637469, Compound 5)
Affinity DataIC50: 17nMAssay Description:Table 1: Experimental steps and methods:a) Compound dilution and plate making1) The compound powder is weighed, dissolved in a certain amount of DMSO...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2026
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Ocumension Therapeutics (Suzhou) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 808964BDBM808964(US12637469, Compound 5)
Affinity DataIC50: 19nMAssay Description:In Vitro Test of the Compound's Inhibitory Effect on VEGFR2 Kinase Experimental Methods and Procedures: The ADP-GLO Kinase Assay is an analytical rea...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2026
Entry Details
US Patent