BDBM808967 US12637469, Compound 8

SMILES CC1(O)CCN(c2ccc(Nc3nc4ccc(-c5cn[nH]c5)cc4n4ccnc34)cc2)CC1

InChI Key InChIKey=VBPBMVOUORRXJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 808967   

TargetTyrosine-protein kinase SYK(Human)
Ocumension Therapeutics (Suzhou) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 808967BDBM808967(US12637469, Compound 8)
Affinity DataIC50: 30nMAssay Description:Table 1: Experimental steps and methods:a) Compound dilution and plate making1) The compound powder is weighed, dissolved in a certain amount of DMSO...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2026
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Ocumension Therapeutics (Suzhou) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 808967BDBM808967(US12637469, Compound 8)
Affinity DataIC50: 31nMAssay Description:In Vitro Test of the Compound's Inhibitory Effect on VEGFR2 Kinase Experimental Methods and Procedures: The ADP-GLO Kinase Assay is an analytical rea...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2026
Entry Details
US Patent