BDBM808976 US12637430, Example 49

SMILES Cc1n[nH]c(C)c1c6ccc(NC(=O)[C@@H](NC(=O)c3ccn(C2CC2)n3)C(C4CC4)C5CC5)cn6

InChI Key InChIKey=ACRIXKPSNBTTME-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808976   

TargetInterleukin-17A(Human)
HitGen

US Patent
LigandChemical structure of BindingDB Monomer ID 808976BDBM808976(US12637430, Example 49)
Affinity DataIC50: 537nMAssay Description:The inhibition of receptor-ligand binding by human IL-17A inhibitors was quantified by competitive ELISA. 0.2 ug/ml of IL-17A (Sino Biological Inc. ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
11/9/2020
Entry Details
US Patent