BDBM81541 US20240140952, Compound 6

SMILES Cc1cnc(nc1Nc2ccc(c(c2)NS(=O)(=O)C(C)(C)C)Cl)Nc3ccc(c(c3)F)C4CCN(CC4)C

InChI Key InChIKey=FPGNUYNSOYSDAN-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 81541   

TargetTyrosine-protein kinase JAK2(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM81541(US20240140952, Compound 6 | US12391676, ID MA9-060)
Affinity DataIC50: 3.30nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM81541(US20240140952, Compound 6 | US12391676, ID MA9-060)
Affinity DataIC50: 11.4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2024
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM81541(US20240140952, Compound 6 | US12391676, ID MA9-060)
Affinity DataIC50: 26nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)