BDBM82556 melatonin, 6-Methoxy

SMILES COc1cc2[nH]cc(CCNC(C)=O)c2cc1OC

InChI Key InChIKey=WRYUMPMURJHKNE-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 82556   

TargetMelatonin receptor type 1B(Human)
The First Affiliated Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM82556(melatonin, 6-Methoxy)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to human MT2 receptor expressed in COS-7 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMelatonin receptor type 1A(Human)
The First Affiliated Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM82556(melatonin, 6-Methoxy)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to human MT1 receptor expressed in COS-7 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMelatonin receptor type 1B(Human)
The First Affiliated Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM82556(melatonin, 6-Methoxy)
Affinity DataKi:  3.5nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT2 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
The First Affiliated Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM82556(melatonin, 6-Methoxy)
Affinity DataKi:  207nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT1 receptor expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetMelatonin receptor(Rabbit)
Rowett Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM82556(melatonin, 6-Methoxy)
Affinity DataKi:  460nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details Article
PubMed