BDBM83339 US20250388583, Compound 599::US20260001879, Compound 7

SMILES Cc1cc2c(C(N)=O)c(N)n(-c3c(C)cc(F)c(O)c3C)c2nc1C

InChI Key InChIKey=RTZAJUVZWJYWOM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 83339   

TargetTyrosine-protein kinase Lck(Human)
Engine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 83339BDBM83339(US20250388583, Compound 599 | US20260001879, Compo...)
Affinity DataIC50: 50nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 83339BDBM83339(US20250388583, Compound 599 | US20260001879, Compo...)
Affinity DataIC50: 50nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetMyelin transcription factor 1(Human)
Wigen Biommedicine Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 83339BDBM83339(US20250388583, Compound 599 | US20260001879, Compo...)
Affinity DataIC50: 200nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent

TargetMyelin transcription factor 1(Human)
Wigen Biommedicine Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 83339BDBM83339(US20250388583, Compound 599 | US20260001879, Compo...)
Affinity DataIC50: 200nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent

TargetMyelin transcription factor 1(Human)
Wigen Biommedicine Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 83339BDBM83339(US20250388583, Compound 599 | US20260001879, Compo...)
Affinity DataIC50: 200nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent