BDBM8336 N-[5-(pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-yl]cyclopropanecarboxamide::pyrazolopyridazine deriv. 16
SMILES O=C(Nc1n[nH]c2nnc(cc12)-c1cccnc1)C1CC1
InChI Key InChIKey=AGSPQSKJPUNTNL-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 8336
Affinity DataKi: 0.0800nM ΔG°: -13.6kcal/molepH: 7.0 T: 22°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
Affinity DataKi: 5nM ΔG°: -11.2kcal/molepH: 7.5 T: 21°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair