BDBM8457 5-{[5-(3,4-dichlorophenyl)furan-2-yl]methylidene}-2-sulfanylidene-1,3-diazinane-4,6-dione::Thiobarbituric acid-furan analogue 22

SMILES O=C1NC(=S)NC(=O)C1=Cc1ccc(-c2ccc(Cl)c(Cl)c2)o1

InChI Key InChIKey=KEFBMBLCSDMBIY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8457   

TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandChemical structure of BindingDB Monomer ID 8457BDBM8457(5-{[5-(3,4-dichlorophenyl)furan-2-yl]methylidene}-...)
Affinity DataIC50: 2.10E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2006
Entry Details Article
PubMed