BDBM8464 5-{[5-(3-chloro-4-methoxyphenyl)furan-2-yl]methylidene}-2-sulfanylidene-1,3-diazinane-4,6-dione::Thiobarbituric acid-furan analogue 29

SMILES COc1ccc(-c2ccc(C=C3C(=O)NC(=S)NC3=O)o2)cc1Cl

InChI Key InChIKey=OYGRQVHOQCOEKH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8464   

TargetLethal factor(Bacillus anthracis)
Burnham Institute

LigandChemical structure of BindingDB Monomer ID 8464BDBM8464(5-{[5-(3-chloro-4-methoxyphenyl)furan-2-yl]methyli...)
Affinity DataIC50: 3.00E+3nMpH: 7.4 T: 2°CAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2006
Entry Details Article
PubMed