BDBM8600 (3-Pyridylmethylene)indane 26a::3-{[(1E)-7-methoxy-2,3-dihydro-1H-inden-1-ylidene]methyl}pyridine

SMILES COc1cccc2CC\C(=C/c3cccnc3)c12

InChI Key InChIKey=VTCRFWNOJMKNRS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 8600   

TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8600(3-{[(1E)-7-methoxy-2,3-dihydro-1H-inden-1-ylidene]...)
Affinity DataIC50: 27nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8600(3-{[(1E)-7-methoxy-2,3-dihydro-1H-inden-1-ylidene]...)
Affinity DataIC50: 955nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8600(3-{[(1E)-7-methoxy-2,3-dihydro-1H-inden-1-ylidene]...)
Affinity DataIC50: 9.74E+3nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed