BDBM9029 Indole-Tacrine Heterodimer 12::N-[6-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)-hexyl]-3-(5-cyano-1H-indol-3-yl)propionamide::N-{6-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl}-3-(5-cyano-1H-indol-3-yl)propanamide

SMILES Clc1ccc2c(NCCCCCCNC(=O)CCc3c[nH]c4ccc(cc34)C#N)c3CCCCc3nc2c1

InChI Key InChIKey=PBSOJOMZHQNAPL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 9029   

TargetAcetylcholinesterase(Bovine)
Neuropharma

LigandPNGBDBM9029(Indole-Tacrine Heterodimer 12 | N-[6-(6-Chloro-1,2...)
Affinity DataIC50:  0.700nMpH: 8.0 T: 30°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM9029(Indole-Tacrine Heterodimer 12 | N-[6-(6-Chloro-1,2...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
Neuropharma

LigandPNGBDBM9029(Indole-Tacrine Heterodimer 12 | N-[6-(6-Chloro-1,2...)
Affinity DataIC50:  11.7nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 405 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed