BDBM92742 NSC332410, 8::US9624235, Compound 8
SMILES C\C(=N/Nc1cc(C)c2ccccc2n1)c1cn(C)n(-c2ccccc2)c1=O
InChI Key InChIKey=SZYFFEIJRPJACM-LFVJCYFKSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 92742
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Pittsburgh
US Patent
University of Pittsburgh
US Patent
Affinity DataIC50: >1.00E+5nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Pittsburgh
US Patent
University of Pittsburgh
US Patent
Affinity DataIC50: >1.00E+5nMAssay Description:In addition to the real-time fluorescence assay for studying inhibition of APE-1 activity, we also employed a gel-based assay to visualize and quanti...More data for this Ligand-Target Pair