BDBM9344 (4R,5S,6S,7R)-4,7-dibenzyl-1-cyclopentyl-5,6-dihydroxy-3-(naphthalen-2-ylmethyl)-1,3-diazepan-2-one::CHEMBL87329::Cyclic Urea 66

SMILES O[C@@H]1[C@@H](O)[C@@H](Cc2ccccc2)N(C2CCCC2)C(=O)N(Cc2ccc3ccccc3c2)[C@@H]1Cc1ccccc1

InChI Key InChIKey=LUZBHUHGIORDFL-WZJLIZBTSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 9344   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM9344((4R,5S,6S,7R)-4,7-dibenzyl-1-cyclopentyl-5,6-dihyd...)
Affinity DataKi:  0.280nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandPNGBDBM9344((4R,5S,6S,7R)-4,7-dibenzyl-1-cyclopentyl-5,6-dihyd...)
Affinity DataKi:  0.280nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed