BDBM96280 4-chloro-N-[(1S,2S)-2-hydroxycyclohexyl]-3-[(5-phenylpyridin-3-yl)ethynyl]benzamide::US12509424, Example 58

SMILES O=C(N[C@H]1CCCC[C@@H]1O)c1ccc(Cl)c(C#Cc2cncc(-c3ccccc3)c2)c1

InChI Key InChIKey=OOQROHBATSAKMK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 96280   

TargetPlatelet-derived growth factor subunit B(Human)
Nippon Shinyaku Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 96280BDBM96280(4-chloro-N-[(1S,2S)-2-hydroxycyclohexyl]-3-[(5-phe...)
Affinity DataIC50: 12nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2026
Entry Details
US Patent