BDBM96285 N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-3-{[5-(pyrazin-2-yl)pyridin-3-yl]ethynyl}benzamide::US12509424, Example 63

SMILES Cc1ccc(C(=O)N[C@H]2CCCC[C@@H]2O)cc1C#Cc1cncc(-c2cnccn2)c1

InChI Key InChIKey=CVVVDXZZAVNTTM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 96285   

TargetPlatelet-derived growth factor subunit B(Human)
Nippon Shinyaku Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 96285BDBM96285(N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-3-{[5-(py...)
Affinity DataIC50: 15nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2026
Entry Details
US Patent