BDBM96628 N-[(1S,2S)-1,3-dihydroxy-1-phenylpropan-2-yl]-4-methyl-3-{[(6-phenylpyrazin-2-yl)amino]methyl}benzamide::US12509424, Example 156

SMILES Cc1ccc(C(=O)N[C@@H](CO)[C@@H](O)c2ccccc2)cc1CNc1cncc(-c2ccccc2)n1

InChI Key InChIKey=JUVOWMBZLYMXMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 96628   

TargetPlatelet-derived growth factor subunit B(Human)
Nippon Shinyaku Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 96628BDBM96628(N-[(1S,2S)-1,3-dihydroxy-1-phenylpropan-2-yl]-4-me...)
Affinity DataIC50: 25nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2026
Entry Details
US Patent