BDBM96633 N-[4-fluoro-3-({[5-(pyrimidin-2-yl)pyridin-3-yl]amino}methyl)phenyl]-N'-[(1R,2S)-2-hydroxycyclohexyl]urea::US12509424, Example 161

SMILES O=C(Nc1ccc(F)c(CNc2cncc(-c3ncccn3)c2)c1)N[C@@H]1CCCC[C@@H]1O

InChI Key InChIKey=MTYHYRHECBFIOS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 96633   

TargetPlatelet-derived growth factor subunit B(Human)
Nippon Shinyaku Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 96633BDBM96633(N-[4-fluoro-3-({[5-(pyrimidin-2-yl)pyridin-3-yl]am...)
Affinity DataIC50: 16nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
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Date in BDB:
5/11/2026
Entry Details
US Patent