BDBM96658 4-fluoro-3-[(Z)-2-fluoro-2-{5-[(oxan-4-yl)amino]pyridin-3-yl}ethenyl]-N-[(1S,2S)-2-hydroxycyclohexyl]benzamide::US12509424, Example 185

SMILES O=C(N[C@H]1CCCC[C@@H]1O)c1ccc(F)c(/C=C(\F)c2cncc(NC3CCOCC3)c2)c1

InChI Key InChIKey=HGDXLMWTJVVXRJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 96658   

TargetPlatelet-derived growth factor subunit B(Human)
Nippon Shinyaku Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 96658BDBM96658(4-fluoro-3-[(Z)-2-fluoro-2-{5-[(oxan-4-yl)amino]py...)
Affinity DataIC50: 5.10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
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Date in BDB:
5/11/2026
Entry Details
US Patent